Dermal Fillers & Injectables
Polynucleotides in London
From £245Regenerative skin-quality treatment that improves hydration, firmness and tone over time.
At a Glance
Polynucleotides — The Essentials
- Treatment Time
- 30–45 minutes
- Downtime
- Minimal (48 hours)
- Results Last
- Maintenance every 6–12 months
- Results Visible
- Gradually over weeks
- Sessions
- Course of 2–3
- Price From
- £245
About the Treatment
What is Polynucleotides?
Polynucleotides are a regenerative treatment that works with the skin's own repair processes to improve hydration, elasticity and overall quality, rather than adding volume.
Delivered as a short course, they are popular for the under-eye area, the face and the neck, with results that build gradually and look entirely natural.
Benefits
Why You'll Love It
- Improves hydration, firmness and skin quality
- Excellent for tired, crêpey under-eyes
- Works with your skin's own repair process
- A gradual, natural-looking glow-up
- Great on its own or with other treatments
- Doctor-led, with a simple treatment course
What to Expect
Your Polynucleotides Journey
- 01
Consultation
A thorough one-to-one assessment of your goals, skin and medical history.
- 02
Bespoke Plan
A personalised plan designed and explained by a GDC-registered practitioner.
- 03
Treatment
Your treatment carried out safely and precisely in our private Mayfair clinic.
- 04
Aftercare
Clear aftercare guidance and a follow-up to support your results.
Gallery
Inside the Clinic
A look at our calm, private Mayfair clinic and the polynucleotides experience.
Results
Before & After
Real client results from our Mayfair clinic. Individual results vary from person to person.
Pricing
Polynucleotides Costs
Prices below are a guide. Your exact plan and cost are confirmed at your consultation.
- Eyes — 1 treatment£245
- Eyes — course of 3£645
- Face or Body — 1 treatment£295
- Face or Body — course of 3£745
- Rejuran Eyes£295
- Rejuran Healer£345
Questions
Frequently Asked
What are polynucleotides?
Polynucleotides are purified chains of DNA fragments, most commonly derived from salmon or trout, that are injected into the skin to support its natural repair and rejuvenation. At our Mayfair clinic we use them to encourage fibroblast activity, hydration and improved skin quality.
What do polynucleotides do for the skin?
They work as a bio-stimulator, helping to improve skin firmness, elasticity, hydration and overall texture over time. Many of our patients choose them for the under-eye area, face and neck to support a fresher, healthier-looking complexion.
How much do polynucleotides cost in London?
Prices start from £245 at our Mayfair clinic, with your exact cost confirmed at your consultation. The final amount depends on the areas treated and the plan we agree together.
How many sessions of polynucleotides will I need?
Most people have a short initial course of two to three sessions spaced around two to four weeks apart, followed by maintenance. We will tailor the number of sessions to your skin at your consultation.
How long do polynucleotide results last?
Results tend to build gradually and are often maintained for several months, particularly with periodic top-up treatments. Longevity varies from person to person depending on skin condition and lifestyle.
Are polynucleotides safe?
Polynucleotides are generally well tolerated and highly purified, and at our clinic every treatment is carried out by an experienced medical practitioner after a full assessment. As with any injectable, we will discuss the possible risks and your suitability at your consultation.
Do polynucleotide injections hurt?
Most people find the treatment comfortable, and we can apply a topical numbing cream beforehand to help. You may feel a mild stinging or pressure as the product is placed.
Is there any downtime after polynucleotides?
Downtime is usually minimal, though you may notice temporary redness, small bumps or mild swelling at the injection points that typically settle within a day or two. We will give you clear aftercare advice to follow.
What is the difference between polynucleotides and dermal filler?
Fillers are designed mainly to add volume and structure, whereas polynucleotides focus on improving the quality and health of the skin itself rather than volumising. Some patients choose to combine the two, which we can discuss at your consultation.
Who is a good candidate for polynucleotides?
They can suit people looking to improve dull, crepey or tired-looking skin, including delicate areas such as under the eyes. The best way to know if they are right for you is a personal assessment at our Mayfair clinic.
Addresses
Concerns This Treatment Helps With
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Learn more →Ready to book your polynucleotides?
Book a consultation with Dr Alexa in Mayfair, or send us a message and we'll be happy to help.
Suitability for any treatment is confirmed during your consultation. Results vary between individuals. This page is for general information and does not constitute medical advice.